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What are the long-term outcomes for patients treated with crenolanib combination therapy?

By Erika Roa

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Eunice WangEunice Wang

Jun 29, 2022

Learning objective: After reading this article, learners will be able to cite a new clinical development in AML


During the 2022 ASCO Annual Meeting, the AML Hub spoke with Eunice Wang, Roswell Park Comprehensive Cancer Center, Buffalo, US. We asked, What are the long-term outcomes for patients treated with crenolanib combination therapy.

What are the long-term outcomes for patients treated with cenolanib combination therapy?

Wang presents the long-term outcomes for patients with newly diagnosed FLT3 mutant disease receiving crenolanib (a FLT3 tyrosine kinase inhibitor) and intensive chemotherapy. Wang outlines the study design, efficacy, and safety results of the long-term, multicenter study. Finally, Wang highlights the ongoing phase III trial, which could yield promising results for younger patients treated with potent second-generation FLT3 inhibitors.